ARF — Fusarium oxysporum Fo47

Summary

FOZG_12544 (ARF) in Fusarium oxysporum Fo47 encodes a small GTPase of the ARF/SAR family, possessing GTPase activity, GTP binding, G protein activity, and protein membrane adaptor functions. The gene is associated with upregulation of ER to Golgi transport, positive regulation of protein exit from ER, vesicle organization, nuclear envelope organization, mitochondrial membrane organization, cell growth mode switching from monopolar to bipolar, mitochondrial fission, membrane organization, cellular response to AOS, regulation of mitotic cytokinesis, positive regulation of mitotic entry, ER to Golgi transport, intracellular protein transport, protein transport, and vesicle transport. The encoded protein localizes to the mitochondria-associated membrane, interphase node, COPII vesicle coat, COPII coated vesicle membrane, ER exit site, division septum, cell cortex of cell tip, cell cortex, Golgi membrane, and cell division site. Related genes in other species link the family to GTPase activity (EC 3.6.5.2) and differential expression during host infection.