CP1 — Fusarium oxysporum Fo47

Summary

FoCP1 (FOZG_13005) from Fusarium oxysporum Fo47 encodes a serine carboxypeptidase belonging to the peptidase S10 family, characterized by the AB hydrolase domain and active-site serine and histidine motifs. The enzyme is annotated with serine carboxypeptidase activity and is associated with proteolysis, phytochelatin anabolism, zymogen activation, and protein catabolism in the vacuole. It localizes to the fungal-type vacuole lumen and extracellular. FoCP1 is linked to cellular responses to nitrogen starvation and has been associated with altered cell death, autophagy, endocytosis, nuclear fusion during mating, prion inheritance, and lifespan. Associations with chemical compound accumulation, protein secretion, and organelle morphology (Golgi, mitochondria) further suggest broad cellular roles. Related genes in other species link the family to apoplastic effector functions and floral organ identity traits.