vrdA — Fusarium oxysporum Fo47

Summary

FOZG_09542 (vrdA) in Fusarium oxysporum Fo47 on chromosome JH717901 encodes a protein with a voltage-gated potassium channel beta-subunit-related domain and an NADP oxidoreductase domain. The gene product exhibits versiconal reductase, versiconal hemiacetal acetate reductase, and hydroxyversicolorone reductase activities, along with general redox activity. It is associated with potassium ion membrane transport and localizes to the monoatomic ion channel complex, cytosol, and nucleus. Studies of related genes in other species link the family to EC 1.1.1.353 and broader oxidoreductase functions, though these associations are not established for vrdA itself.