FBP1 — Fusarium oxysporum Fo47

Summary

FOZG_07637 (FBP1) in Fusarium oxysporum Fo47 encodes a fructose-1,6-bisphosphatase, a class-1 FBPase enzyme with fructose 1,6-bisphosphate 1-phosphatase activity and metal binding. This gene is associated with gluconeogenesis, sucrose anabolism, fructose metabolism, and the metabolic burst, as well as defense response and cellular response to glucose starvation. It is linked to cytoplasmic, cytosolic, and nuclear localization. Phenotypic associations include abnormal pseudohyphal growth, increased entry into G0 stationary phase, increased hydrostatic pressure resistance, increased pheromone sensitivity, decreased utilization of nitrogen sources, and increased respiratory metabolism, among many others. Studies of related genes in other species connect the FBP1 family to oxidative stress response.