TRI13 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G08573, symbol TRI13 on chromosome 1 of Fusarium graminearum PH-1, encodes a cytochrome P450 monooxygenase. This enzyme possesses oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen, monooxygenase activity, and binds heme, iron, and other metals. The gene is associated with fumonisin anabolism, mycotoxin anabolism, small molecule biosynthesis, sexual reproduction, translation elongation, and fermentation. The encoded protein is localised to the endoplasmic reticulum and membrane. Related genes in other species are linked to similar oxidative functions, but the specific roles in fumonisin and mycotoxin production are established for TRI13 itself.