TRI13 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G08523, designated TRI13 on chromosome 1 of Fusarium graminearum PH-1, encodes a cytochrome P450 monooxygenase with aromatase, NADPH-hemoprotein reductase, monooxygenase and oxidoreductase activities, binding heme, iron, FMN and FAD. The gene is associated with mycotoxin anabolism, small molecule biosynthesis, sexual reproduction, translation elongation, fermentation, and localisation to the membrane and cytosol. It is also linked to the sphH protein. Studies of related genes in other species connect the cytochrome P450 family to additional monooxygenase functions and EC classes 1.14.14.1 and 1.6.2.4.