FAD1 — Fusarium graminearum PH-1

Summary

FgFAD1 (FAD1, NAD1) on chromosome 1 of Fusarium graminearum PH-1 encodes a protein with FMN adenylyltransferase activity, ATP and metal binding, and hydrolase activity, placing it in the PAPS_reduct and Rossmann-like α/β/α fold families. The gene is associated with FMN metabolism, FAD biosynthesis, differential growth, and innate immunity, and its product localises to mitochondria, cytosol, and nucleus. Related genes in other species are linked to FAD synthase activity (EC 2.7.7.2) and to pathogens such as Verticillium dahliae and Fusarium oxysporum pathovars.