GOA1 — Candida albicans

Summary

C4_04640C_A (GOA1) on Candida albicans chromosome 4 encodes a protein of unknown molecular function, with no enzyme class or EC number assigned. The gene is associated with a wide range of biological processes, including mitochondrial localization, mtDNA replication, ATP and cAMP anabolism, cellular respiration, the glyoxylate cycle, gluconeogenesis, and mannan anabolism. It is linked to traits relevant to fungal pathogenesis, such as cytokine production (including IL22), innate immunity, immune evasion, disruption of host phagocytosis, and programmed cell death. Additionally, GOA1 is associated with cell size control, chlamydospore formation, and nucleotide anabolism. The product localizes to both mitochondria and cytoplasm.