FAD1 — Candida albicans

Summary

C1_08650C_A (FAD1, also known as NAD1 or CaNAD1) in Candida albicans chromosome 1 encodes a protein with FMN adenylyltransferase activity (EC 2.7.7.2). The product also exhibits hydrolase activity, binds ATP and magnesium, and belongs to the PAPS_reduct and Rossmann-like_a/b/a_fold domain families. This gene is associated with FAD and FMN metabolism, ATP biosynthesis, polyamine transport, endocytosis, cell killing, and innate immunity. The protein localizes to mitochondria, cytosol, and nucleus. Studies of related genes in other species, including Fusarium oxysporum and Verticillium dahliae, link the FAD1 family to FAD synthase activity, though these associations are not established for this specific gene.