gal4 — Aspergillus nidulans FGSC A4

Summary

ANIA_11185 (gal4) on chromosome 6 of Aspergillus nidulans FGSC A4 encodes a Zn(II)2Cys6 transcription factor with DNA-binding transcription activator activity specific to RNA polymerase II. The gene is associated with positive regulation of thiamin biosynthetic process, nitrate assimilation, and upregulation of transcription by galactose. It has also been linked to RNA-dependent gene silencing, aflatoxin and sterigmatocystin anabolism, and positive regulation of metabolism. The encoded protein localises to the cytoplasm, cytosol, and nucleus. Studies of related genes in other species link the family to C6 transcription factor function.