hxnR — Aspergillus nidulans FGSC A4

Summary

ANIA_11197 (hxnR) on chromosome 6 of Aspergillus nidulans FGSC A4 encodes a transcription factor with a VerF-like domain. The gene product is annotated as an RNA polymerase II-specific DNA-binding transcription activator and is associated with the regulation of transcription, including both positive and negative regulation by RNA polymerase II. hxnR is associated with nicotinate breakdown, genetic transfer, and the regulation of fungal-type cell wall organization. The protein localizes to the nucleus, nucleolus, chromatin, and mitotic spindle. Related genes in other species, such as those in Fusarium oxysporum, encode C2H2-type domain-containing proteins, though these associations are not established for hxnR itself.