PSD2 — Aspergillus nidulans FGSC A4

Summary

ANIA_07385 (PSD2) on chromosome 4 of Aspergillus nidulans FGSC A4 encodes a phosphatidylserine decarboxylase, a member of the PS_Dcarbxylase family, with phosphatidylserine decarboxylase activity and L-tryptophan decarboxylase activity, and binds phospholipids and metals. The gene is associated with phosphatidylserine, phosphatidylethanolamine, phosphatidylcholine, and phospholipid anabolism, as well as protein autoprocessing, psilocybin biosynthesis, biofilm formation, and filamentous growth in response to chemical, starvation, and biotic stimuli. Its product localises to the Golgi stack and membrane, endosome and fungal-type vacuole membranes, mitochondria, cytosol, and the cell division site. PSD2 is also linked to quantum yield. Studies of related genes in other species connect the family to phosphatidylserine decarboxylase (EC 4.1.1.65) and phosphatidylserine decarboxylase proenzyme (EC 4.1.1.105) activities.