AMT1 — Aspergillus nidulans FGSC A4

Summary

ANIA_07463 (AMT1, also known as AnAMT1, MEP1, MEP2, and MEAA) on chromosome 4 of Aspergillus nidulans FGSC A4 encodes an ammonium transporter family protein with ammonium channel and methylammonium transmembrane transporter activity. The gene is associated with ammonium import across the plasma membrane, ammonium membrane transport, and nitrogen utilization. The encoded protein localizes to the plasma membrane, fungal-type vacuole, and Golgi complex. AMT1 is linked to numerous phenotypes including abnormal biofilm formation, increased sporulation, increased virulence, altered cell cycle progression, abnormal autophagy and pexophagy, decreased nitrogen source utilization, and abnormal respiratory metabolism. Studies of related genes in other species link the family to traits such as protein and phosphate content.