ACUK — Aspergillus nidulans FGSC A4

Summary

ANIA_07468 (ACUK, AnACUK) on chromosome 4 of Aspergillus nidulans FGSC A4 encodes a Zn2Cys6 DNA-binding transcription factor with a PAS domain, belonging to the ERT1/acuK gluconeogenic transcription factor family. The gene product is annotated as a sequence-specific DNA-binding transcription factor that localises to the nucleus and binds zinc. AnACUK is associated with carbon catabolite repression, gluconeogenesis, the glyoxylate cycle, acetate metabolism, the TCA cycle, alternative respiration, heterotrophy, cellular response to starvation, detoxification, and positive regulation of metabolism. Studies of related genes in other species link the family to transcriptional activation of gluconeogenesis.