RGSA — Aspergillus fumigatus
Summary
AFU6G06860 (RGSA, AfRGSA) on Aspergillus fumigatus chromosome 6 encodes a regulator of G protein signaling (RGS) domain protein with GTPase-activating protein (GAP) activity. It is associated with negative regulation of G protein-coupled receptor (GPCR) signaling pathways, asexual sporulation, spore germination, and secondary metabolism. The protein localizes to the internal side of the plasma membrane. Related genes in other species link the family to infection processes.
Annotations
- Chromosome
- 6
- Related genes
- rgsA, RGSA
- GO terms
- Sporulation, GAP activity, internal side of plasma membrane, negative regulation of GPCR protein signaling pathway, Asexual Sporulation, secondary metabolism, Spore Germination
- Publications
- PMID:17139616, PMID:15944355, PMID:23002107, PMID:22634273, PMID:31717953, PMID:16546420, PMID:15228532
- Traits
- increased virulence (hypervirulence)