RODA — Aspergillus fumigatus

Summary

AFU5G09580, symbol RODA (AfRODA) in Aspergillus fumigatus on chromosome 5, encodes a hydrophobin family protein and is a structural constituent of the cell wall. The gene is associated with asexual spore wall assembly, spore dispersal, conidium germination, and asexual sporulation. It is linked to the spore wall and fungal-type cell wall, as well as extracellular localisation. RODA has been associated with MIP2 production, cytokine production, inflammatory and immune responses, phagocytosis, and immune evasion, including symbiont-mediated suppression of host neutrophil extracellular trap formation. Additional associations include melanin anabolism, interaction with host, memory, vision, nuclear import, and translation elongation. Related genes in other species link the hydrophobin family to sporogenesis.