AZGA — Aspergillus fumigatus

Summary

AFU5G09750, designated AZGA (azgA) in Aspergillus fumigatus on chromosome 5, encodes a putative nucleoside transporter belonging to the Azg-like and NCS2 protein families. The gene product possesses guanine and adenine transmembrane transporter activity and is associated with purine base transport, specifically adenine and guanine import into the cell. AZGA localises to the endomembrane system, Golgi membrane, Golgi complex, and plasmalemma. Studies of related genes in other species link the family to protein content traits, though this association has not been established in A. fumigatus.