MDR4 — Aspergillus fumigatus

Summary

AFU5G09480 (MDR4) on Aspergillus fumigatus chromosome 5 encodes a putative ABC transporter of the ABCA subfamily, possessing ATP hydrolase activity, ATP binding, and ATP-coupled transmembrane transporter activity, with annotated lipid carrier activity and ABC-type oligopeptide transporter function. The gene is associated with oligopeptide export from the mitochondrion, lipid transport, sterol anabolism, biofilm formation, homologous recombination, sporulation, hyphal growth, and cell cycle processes. Its product localises to the mitochondrial inner membrane, plasmalemma, and membrane generally. Related genes in other species, including Fusarium oxysporum and Verticillium dahliae, are linked by sequence similarity to this gene.