CDA — Aspergillus fumigatus

Summary

AFU3G07210, also known as CDA, encodes a putative polysaccharide deacetylase with chitin deacetylase activity and chitin binding capability, supported by its NODB domain and metal-binding properties. This enzyme is associated with chitin breakdown, chitosamine metabolism, and polysaccharide degradation, and is linked to cell wall organization and carbohydrate metabolism. The gene is associated with immune evasion. The protein is localized to the extracellular space. Studies of related genes in other species link the family to the broader deacetylase enzyme class (EC 3.5.1.41), though this specific activity is not yet established for AFU3G07210 itself.

Annotations

Chromosome
3
Related genes
cda
GO terms
chitosamine metabolism, Chitin Deacetylase Activity, metal binding, extracellular, Cell Wall Organization, polysaccharide breakdown, carbohydrate metabolism, chitin breakdown
Publications
PMID:1937806, PMID:36675900, PMID:19146970, PMID:27901067, PMID:31602821, PMID:32117802, PMID:19760058, PMID:28496100