prtT — Aspergillus fumigatus

Summary

AFU3G06050 (symbol prtT) on chromosome 3 of Aspergillus fumigatus encodes a fungal-specific transcription factor containing a Zn2Cys6 DNA-binding domain. The product exhibits DNA-binding transcription factor activity specific to RNA polymerase II and localises to the nucleus. This gene is associated with the positive regulation of growth of a unicellular organism as a thread of attached cells, oligopeptide transport, growth of a unicellular organism as a thread of attached cells, upregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus, filamentous growth of a population of unicellular organisms in response to biotic stimulus, protein breakdown, ergosterol anabolism, secretion, proteolysis, cell death, and DNA-dependent transcription. Related genes in other species encode Zn2Cys6 transcription factors, though these associations are not yet established for A. fumigatus.