maiA — Aspergillus fumigatus

Summary

AFU2G04240 (maiA) on chromosome 2 of Aspergillus fumigatus encodes a maleylacetoacetate isomerase, a glutathione S-transferase family enzyme with EC 5.2.1.2 activity. The protein contains GST_Zeta_N, GST_Zeta_C, and glutathione S-transferase domains. It is associated with tyrosine and L-phenylalanine breakdown, glutathione metabolism, and homeostasis, and is localized to mitochondria. The gene is linked to the MAIA family. Studies of related genes in other species connect the family to glutathione S-transferase activity (EC 2.5.1.18), though these associations are not established for A. fumigatus.