NIIA — Aspergillus fumigatus

Summary

AFU1G12840 (NIIA, niiA) in Aspergillus fumigatus encodes a nitrite reductase (NADPH) (EC 1.7.1.4) that binds 2Fe-2S and 4Fe-4S clusters, FAD, NADP, and heme. This gene is associated with nitrate assimilation, anaerobic respiration, cellular respiration, arginine metabolism, siderophore and gliotoxin anabolism, ergosterol anabolism, polysaccharide metabolism, cell wall biogenesis, hyphal growth, sporulation, morphogenesis, metal ion transport, detoxification, regeneration, homeostasis, and the mitotic cell cycle. Related genes in other species link the NIIA family to nitrate uptake.