KDX1 — Verticillium dahliae
Summary
VdKDX1 (VDAG_02584) on chromosome DS572698 of Verticillium dahliae encodes a mitogen-activated protein kinase (MAPK) with serine/threonine kinase activity (EC 2.7.11.24), belonging to the ERK1 subfamily. It is associated with regulation of melanin and chitin anabolism, cell wall organization, chemotropism, calcium-mediated signaling, thermotolerance, and the pheromone response MAPK cascade. The gene is linked to abnormal carbon source utilization, altered sporulation, and cell cycle progression defects. It localizes to the cytoplasm, nucleus, mitotic spindle pole body, and cell division site. Related genes in other species connect it to cell integrity signaling, turgor pressure, germination rate, and pathogenicity traits including loss of virulence and hypervirulence.
Annotations
- Chromosome
- DS572698
- Related genes
- AT1G07880, AT5G56580, YER109C, TLC1, KDX1, ZDS1, PBS2, MIH1
- GO terms
- protein kinase A activation, Cell Death, genetic transfer, Biological_Process, ATP Binding, Nucleus, Protein Serine/threonine Kinase Activity, Fungal-type Cell Wall Organization
- Publications
- 28357323, 9742128, 19822674, 8196622, 27840029, 9491072, 11779796, 28383696
- Traits
- RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, STRESS RESISTANCE: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, CELL CYCLE PROGRESSION: ABNORMAL, NUCLEAR POSITION: ABNORMAL, ENTRY INTO G0 (STATIONARY PHASE): INCREASED