BSC1 — Neurospora crassa

Summary

NCU09197 (BSC1) of Neurospora crassa encodes a Myb-like DNA-binding domain protein with RNA polymerase II- and III-specific transcription factor activity, localising to the nucleus, membrane, cytosol, spliceosome and SNAPc complexes. It is associated with regulation of DNA re-duplication, snRNA transcription, cell cycle G1/S phase transition, stomatal complex patterning, flocculation, cichorine anabolism, mRNA splicing, activation of salinity response, multicellular organismal water homeostasis, and response to lipid. Phenotypic associations include abnormal or absent flocculation and biofilm formation, increased rate of entry into G0, premature G1/S transition, delayed cytokinesis, increased polyploidy, increased adhesion and mating efficiency, and absent toxin, osmotic and oxidative stress resistance. Studies of related genes in other species link the family to flocculin and adhesion domains, and to traits such as beta-glucan and polysaccharide content.