EXG12 — Neurospora crassa

Summary

NCU08755, also known as EXG12 or gh3-3, encodes a glycoside hydrolase family 3 protein with beta-glucosidase activity (EC 3.2.1.21). The product contains Glyco_hydro_3_N and Glyco_hydro_3_C domains, an Fn3-like domain, and is classified as a cellulose-degrading GH3 enzyme. This gene is associated with carbohydrate, glucan, and cellulose breakdown, and its product is localised to the extracellular space. Studies of related genes in other species, including cellobiase cel3A and sequences from Fusarium and Verticillium species, link the family to plant cell wall degradation.