NIRA — Neurospora crassa
Summary
NCU08294 (NIRA, nit-4) on Neurospora crassa chromosome 4 encodes a Zn2Cys6 DNA-binding transcription factor that binds sequence-specific DNA and regulates RNA polymerase II transcription. The gene is associated with nitrate assimilation, nitrogen utilization, nitrogen catabolite repression, and positive regulation of transcription initiation. It is also linked to chromatin modeling and catabolite repression. The encoded protein localizes to both the nucleus and cytosol. Studies of related genes in other species connect the family to nitrate uptake.
Annotations
- Chromosome
- 4
- Related genes
- NIRA, nirA
- GO terms
- Catabolite Repression, Regulation Of Nitrate Assimilation, Sequence-specific DNA Binding, DNA-binding Transcription Factor Activity, RNA Polymerase II-specific, Zn binding, Nucleus, DNA Binding, DNA-dependent transcription
- Publications
- PMID:7565720, PMID:20507451, PMID:10394902, PMID:1538701, PMID:7592378, PMID:8121403, PMID:18673441, PMID:8662212
- Traits
- nitrate uptake