CAT8 — Neurospora crassa

Summary

NCU06656 (NcCAT8, also known as acu-15) on Neurospora crassa chromosome 5 encodes a Zn2Cys6 fungal-type DNA-binding domain transcription factor with DNA-binding transcription repressor activity, RNA polymerase II-specific. The gene is associated with regulation of gene expression and DNA-templated transcription, including both positive and negative regulation of transcription by RNA polymerase II. It is associated with the glyoxylate cycle, fermentation, cellobiose metabolism, purine base breakdown, and filamentous growth in response to biotic stimulus. The encoded protein localizes to the nucleus, cytosol, and membrane. Related genes in other species link this gene family to regulation of carbon metabolism and acetate utilization pathways.