SLN1 — Neurospora crassa

Summary

NCU06680 (SLN1, NcSLN1) on Neurospora crassa chromosome 5 encodes an F-box domain-containing protein. The gene is associated with glycerol anabolism, MAPK cascade signaling, and signal transduction. Phenotypic associations link SLN1 to osmotic stress responses, including decreased resistance to hypo-osmotic stress and absent resistance to hyper-osmotic stress, as well as altered cell cycle progression, such as G1/S phase arrest and increased G2/M transition. Additional associations include decreased cell fusion, cytokinesis, and chitin deposition, increased respiratory metabolism, and altered endoplasmic reticulum and Golgi distribution. Related genes in other species are associated with histidine kinase domains and are linked to turgor pressure and oxidative stress response.