plc-1 — Neurospora crassa

Summary

NCU06245, symbol plc-1, on Neurospora crassa chromosome 3, encodes a phosphatidylinositol-4,5-bisphosphate phospholipase C (EC 3.1.4.11) containing EF-hand, C2, and PLC catalytic domains. The enzyme has calcium ion binding activity and is associated with phosphoinositide-mediated signaling, inositol phosphate anabolism, cytosolic release of stored calcium, calcium signaling, pigmentation, protein secretion, lipolysis, cellulose breakdown, hypersensitivity, and homeostasis. It is linked to carotenoid content and localizes to the cytoplasm, cytosol, and nucleus.