pytC — Neurospora crassa

Summary

NCU05832 (pytC) on Neurospora crassa chromosome 7 encodes a SAM-dependent methyltransferase superfamily protein with methyltransferase activity. The gene is associated with regulation of secondary metabolism, including secondary metabolite biosynthesis and activation of gliotoxin anabolism, as well as disruption of host phagocytosis, spore formation, hypersensitivity, membrane transport, methylation, and DNA-dependent transcription. It is linked to oxidative stress response and localises to the nucleus. Studies of related genes in other species connect the family to S-adenosyl-L-methionine-dependent methyltransferase activity (EC 2.1.1.-).