EGT2 — Neurospora crassa

Summary

NcEGT2 (EGT2) of Neurospora crassa on chromosome 6 encodes a protein. The gene is associated with ergothioneine anabolism, cell polarization, morphogenesis, cell growth, fermentation, and amino acid anabolism. It is associated with numerous phenotypes including decreased cell cycle progression, increased polyploidy, increased fermentative growth, delayed meiotic recombination, abnormal vesicle and Golgi distribution, abnormal bud neck morphology and septum formation, decreased chromosome segregation, decreased radiation and hyperosmotic stress resistance, increased freeze-thaw resistance, and abnormal chitin deposition. The gene is also linked to normal cell shape and size, normal G1 phase progression, and normal autophagy and pexophagy. Studies of related genes in other species connect the family to abnormal budding and increased biofilm formation.