qa-1S — Neurospora crassa

Summary

NCU06027 (qa-1S) on Neurospora crassa chromosome 7 encodes a protein with 3-dehydroquinate synthase, 3-phosphoshikimate 1-carboxyvinyltransferase, shikimate kinase, shikimate 3-dehydrogenase (NADP+), and 3-dehydroquinate dehydratase activities, along with DNA and ATP binding. The gene is associated with the shikimate pathway, aromatic amino acid biosynthesis, quinate breakdown, carbon catabolite repression, negative regulation of transcription by RNA polymerase II, and metabolism of sucrose, pyruvate, isoleucine, and TCA cycle intermediates. It is linked to cytoplasmic localization. Related genes in other species connect the family to shikimate and quinate metabolism.