CKK2 — Neurospora crassa

Summary

NCU06177, designated CKK2 (also known as camk-3) on Neurospora crassa chromosome 3, encodes a protein with a protein kinase domain and serine/threonine kinase active site, and is annotated with calcium/calmodulin-dependent kinase activity, protein kinase A activity, calmodulin binding, phospholipid binding, protein kinase activity, protein serine kinase activity, protein serine/threonine kinase activity, identical protein binding, and ATP binding. The gene is associated with mitotic cytokinesis site selection, negative regulation of calcineurin-mediated signaling, meiotic G2/MI DNA replication checkpoint, positive regulation of cell cycle switching from mitotic to meiotic, negative regulation of cytoplasmic translation, negative regulation of inositol phosphate biosynthesis, single-species surface biofilm formation, regulation of invasive growth in response to glucose limitation, negative regulation of pseudohyphal growth, positive regulation of mitotic cytokinesis site selection, upregulation of gluconeogenesis, CAMKK-AMPK signaling cascade, positive regulation of pseudohyphal growth, fungal-type cell wall assembly, plasma membrane organization, septin ring assembly, negative regulation of translation, and cell growth mode switching from monopolar to bipolar. It localizes to the non-growing cell tip, cell cortex of non-growing cell tip, perinuclear space, new growing cell tip, nucleotide-activated protein kinase complex, cellular bud neck septin ring, septin ring, cell cortex of growing cell tip, and microtubule