qa-3 — Neurospora crassa

Summary

NCU06025, designated qa-3 on Neurospora crassa chromosome 7, encodes a shikimate dehydrogenase family protein with quinate:NAD 3-oxidoreductase activity (EC 1.1.1.24). The gene is associated with the shikimate pathway, quinate breakdown, protocatechuate anabolism, and aromatic amino acid family anabolism, as well as isoleucine breakdown, sucrose metabolism, pyruvate metabolism, the TCA cycle, translation initiation, and digestion. It is linked to amino acid content and localises to the cytoplasm. Studies of related genes in other species connect the family to additional shikimate-pathway enzymes such as shikimate kinase (EC 2.7.1.71) and 3-dehydroquinate dehydratase (EC 4.2.1.10).