ZC220 — Neurospora crassa
Summary
NCU04866 (ZC220, ada-6) on Neurospora crassa chromosome 4 encodes a Zn2Cys6 DNA-binding transcription factor, a member of the fungal-specific Zn(II)2Cys6 binuclear cluster family. The product possesses sequence-specific DNA-binding and RNA polymerase II-specific transcription factor activity, localises to the nucleus, and binds zinc and pigment. The gene is associated with positive regulation of transcription and metabolism, calcium signalling, sphingolipid anabolism, membrane transport, signal transduction, and hypersensitivity. It has also been connected to the oxidative stress response. Related genes in other species, including Fusarium oxysporum, encode Zn2Cys6 transcription factors.
Annotations
- Chromosome
- 4
- Related genes
- ADA-6
- GO terms
- Hypersensitivity, Sequence-specific DNA Binding, DNA-binding Transcription Factor Activity, RNA Polymerase II-specific, Zn binding, Nucleus, DNA Binding, DNA-dependent transcription, Positive Regulation Of Transcription By RNA Polymerase II
- Publications
- PMID:20952652, PMID:22001287, PMID:19111642, PMID:20148857, PMID:25701285, PMID:23001671, PMID:22562164, PMID:16283302
- Traits
- oxidative stress response