NIIA — Neurospora crassa

Summary

NCU04720 (NIIA, nit-6) on Neurospora crassa chromosome 6 encodes a protein with multiple domains, including Rieske 2Fe-2S, 4Fe-4S, siroheme, FAD/NAD-binding, and BFD-like domains. The enzyme is annotated with nitrite reductase activity, redox activity, and binding of 2Fe-2S, 4Fe-4S, heme, FAD, and NADP. This gene is associated with nitrate assimilation, anaerobic respiration, nitrogen catabolite repression, catabolite repression, siroheme anabolism, regulation of gene expression, digestion, conidia formation, and spore formation. Studies of related genes in other fungi link the family to nitrate uptake.