chlE — Neurospora crassa

Summary

NCU02679 (chlE) on Neurospora crassa chromosome 1 encodes a carboxylesterase with chlorogenate hydrolase, carboxylesterase, and carboxylic ester hydrolase activities, belonging to the carboxylesterase B and alpha/beta hydrolase families. The gene is associated with cholesterol metabolism, iron transport, lipolysis, and lipid metabolism, and its product is localized extracellularly. Related genes in other species link the family to activities including 3.1.1.42, 3.1.1.1, and 3.1.1.3, and to plant pathogens such as Verticillium dahliae and Fusarium oxysporum.