ACUD — Magnaporthe oryzae 70-15

Summary

MGG_04895 (symbol ACUD, also known as ICL1) in Magnaporthe oryzae 70-15 encodes an isocitrate lyase, an enzyme with isocitrate lyase and methylisocitrate lyase activities that also binds metal ions. The gene is associated with the glyoxylate cycle, the TCA cycle, acetate and fatty acid breakdown, propionyl-CoA anabolism, and glyoxysomal and peroxisomal localisation. It is linked to appressorium formation, invasive growth, melanin anabolism, ascus development, autophagy, cell death, detoxification, translation initiation, and heterotrophy. Associations with rice blast disease and with Oryza sativa are also recorded. Phenotypic associations include altered vegetative growth, cell cycle progression, sporulation, stress resistance (cold, osmotic, alkaline, hydrostatic pressure), apoptosis, mitochondrial genome maintenance, and carbon and nitrogen source utilisation. Related genes in other species link the family to survival rate in stationary phase.