TIF — Magnaporthe oryzae 70-15

Summary

MGG_04885 (TIF, also known as FAL1) in Magnaporthe oryzae 70-15 encodes a DEAD/DEAD-box RNA helicase with ATP hydrolase activity, mRNA binding, and RNA binding functions, classified as EC 3.6.4.13. The gene is associated with defense response, innate immunity, immune response, mRNA splicing via the spliceosome, homologous recombination, hyphal growth, signal transduction, and rRNA processing. It localizes to the catalytic step 2 spliceosome and nucleolus. Phenotypic associations include abnormal chemical compound excretion, increased vacuolar transport, decreased RNA localization, absent peroxisomal transport, absent apoptosis, absent mitotic recombination, decreased cell cycle progression in M phase, premature cell cycle progression through G1/S phase transition, delayed exit from G0, absent anaerobic growth, and abnormal fermentative metabolism. Studies of related genes in other species link the family to protein content traits.