ABC2 — Magnaporthe oryzae 70-15

Summary

MoABC2 (MGG_04855) on chromosome 3 of Magnaporthe oryzae 70-15 encodes an ABC transporter of the ABC7 family, possessing ATP hydrolase activity and annotated with cadmium ion, haem-transporting, phytochelatin and xenobiotic transporter activities, as well as heme binding. The protein localises to the vacuolar membrane, fungal-type vacuole, Golgi complex and plasma membrane. It is associated with haem export from vacuole to cytoplasm, cellular detoxification of cadmium ions, glutathione and PC2 import into vacuole, xenobiotic detoxification, response to toxic substances and metals, siRNA-mediated post-transcriptional gene silencing, host invasion, cell wall biogenesis, filamentous growth in response to starvation, secondary metabolism, and cichorine biosynthesis. Related genes in other species are linked to oxidative and osmotic stress resistance, vacuolar morphology, endocytosis, cell cycle progression, and prion inheritance.