PEP8 — Magnaporthe oryzae 70-15

Summary

MGG_04830 (PEP8, MoPEP8) on chromosome 2 of Magnaporthe oryzae 70-15 encodes a vacuolar protein sorting-associated protein 26B-B, a member of the Vps26-related and arrestin-like_C domain families, with protein transporter activity. The gene is associated with retromer complex, endosome, and CROP complex localization, and is linked to retrograde transport from endosome to Golgi, autophagy, intracellular protein transport, and protein-Golgi retention. It is associated with appressorium-mediated host invasion, host invasion, pigmentation, asexual reproduction, chitin anabolism, morphogenesis, mitotic cell cycle, and cell cycle processes. Phenotypic associations include abnormal filamentous growth, absent endocytosis, increased adhesion, altered cell cycle progression, abnormal septum and spore wall formation, and increased ionic stress resistance. Studies of related genes in other species link the gene to VPS35 and RIM101.