FLS — Lactuca sativa

Summary

LsFLS, on chromosome 8 of garden lettuce (Lactuca sativa), encodes a protein with domains including IPNS-like_FE2OG_OXY, DIOX_N, Oxoglu/Fe-dep_dioxygenase, and IPNS-like_sf, and has leucocyanidin oxygenase, naringenin-chalcone synthase, flavanone 4-reductase, dihydroflavanol 4-reductase, flavonol synthase, and flavanone 3-dioxygenase activities, and binds vitamin C and metals. The gene is associated with flavonol, anthocyanin, chalcone, coumarin, and secondary metabolite biosynthesis, as well as regulation of phenylpropanoid and anthocyanin metabolism. It is linked to responses to UV-B, light, cold, wounding, oxidative stress, jasmonic acid, auxin, gravity, and fungal molecules. Associations include flavonoid and anthocyanin content, photosynthetic rate, respiration rate, stomatal closure, root morphology, adventitious root formation, herbicide sensitivity, insect damage response, flower development, pollen fertility, and salt, drought, and low-temperature stress tolerance. The protein localizes to the cytosol, nucleus, endoplasmic reticulum, and tonoplast.