ATM4 — Lactuca sativa

Summary

LsATM4, also known as ATM4, is a garden lettuce gene on chromosome 8 that encodes a MYB-domain transcription factor with DNA-binding, transcription factor activity, and protein dimerization activity. It is associated with the regulation of anthocyanin, proanthocyanidin, flavonoid, and glucosinolate biosynthesis, as well as raffinose metabolic processes, trichome morphogenesis and spacing, and defense responses to insects. The gene is linked to drought recovery, cadmium detoxification, sulfur starvation response, and cutin anabolism. It localizes to the nucleus, cytosol, root hair, and preprophase band. Associations with agronomic traits include leaf trichome density, seed protein content, shoot elongation under submergence, phosphorus response, iron concentration, and photoperiod-sensitive flowering time. Studies of related genes in other species connect the family to cuticle development, suberin deposition, glucosinolate accumulation, and drought response.