ADH — Lactuca sativa

Summary

LSAT_V11C800443780 (ADH) on garden lettuce chromosome 8 encodes a protein with S-(hydroxymethyl)glutathione dehydrogenase (NADP+), S-(hydroxymethyl)glutathione dehydrogenase (NAD+), aryl-alcohol dehydrogenase (NADP+), enone reductase, S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+], 2-alkenal reductase (NADPH), cinnamyl-alcohol dehydrogenase, aldo-keto reductase (NAD), protein homodimerization, and zinc binding activities. The gene is associated with responses to hypoxia, flooding, cold, hydrogen peroxide, sucrose, estradiol, caffeine, and bacteria, as well as methanal catabolism, cellular respiration, isoprenoid and lignin anabolism, green leaf volatile biosynthesis, and the hypersensitive response. It has been linked to submergence tolerance, drought tolerance, salt tolerance, low temperature stress response, herbicide sensitivity, disease tolerance, photosynthetic rate, and respiration rate. The protein localizes to the chloroplast (stromule, thylakoid, envelope, stroma), apoplast, cytosol, plasmalemma, and nucleus. Studies of related genes in other species connect the family to hypoxia tolerance, freezing tolerance, anaerobic response, and fruit aroma.