HMA1 — Lactuca sativa

Summary

LsHMA1, encoded by the gene LSAT_V11C800437270 on chromosome 8 of garden lettuce (Lactuca sativa), is a P-type ATPase with heavy-metal-associated domains and annotated copper, zinc, cadmium, potassium, and sodium transporter activities. It is associated with detoxification of copper, zinc, and cadmium ions, as well as copper and zinc ion homeostasis and transport, response to cobalt ion, and regulation of root morphogenesis. The gene has been connected to traits including copper sensitivity, drought tolerance, high temperature stress response, oxidative stress response, disease tolerance, leaf morphology, root length, plant height, flowering time, germination rate, and stomatal opening and closure. Related genes in other species link the family to chloroplast copper delivery, photosynthesis under high light, and heavy metal tolerance.