HMG1 — Lactuca sativa
Summary
LsHMG1 (HMG1) on chromosome 8 of garden lettuce encodes a hydroxymethylglutaryl-CoA reductase (HMGR). This gene is associated with the MVA pathway, CoA metabolism, and the biosynthesis of sterols, triterpenoids, isoprenoids, saponins, terpenoids, and phenylpropanoids. It is linked to responses to jasmonic acid and is localized to multiple membranes including the ER, plastid, peroxisome, and chloroplast. Associations with plant height, biomass, flowering time, senescence, male fertility, photosynthetic rate, and defense responses have been observed. Studies of related genes in other species connect the HMGR family to isoprenoid biosynthesis, phytosterol content, disease resistance, and fruit development.
Annotations
- Chromosome
- 8
- Related genes
- HMG1, HMG2
- GO terms
- phenylpropanoid anabolism, Chloroplast Membrane, terpenoid anabolism, Mitochondrial Membrane, Response To Jasmonic Acid, isoprenoid anabolism, peroxisome membrane, Hydroxymethylglutaryl-CoA Reductase (NADPH) Activity
- Publications
- 9245257, 20865301, 12198192, 11114204, 21601648, 26015445, 23572922, 20736450
- Traits
- mevalonate pathway regulation, isoprenoid biosynthesis, mevalonate synthesis, enzyme activity regulation, light response, Reduced Sterol and Triterpenoid Levels, Root Elongation Inhibition, Dwarf, Sterile, Rapid Leaf Senescence, plant development