GAO1 — Lactuca sativa
Summary
LSAT_V11C800435990, designated GAO1, on garden lettuce (Lactuca sativa) chromosome 8, encodes a cytochrome P450 protein. The enzyme exhibits amorpha-4,11-diene 12-monooxygenase and germacrene A hydroxylase activities, along with general monooxygenase and oxidoreductase functions dependent on heme and iron binding. GAO1 is associated with sesquiterpene, terpenoid, lactone, and phenylpropanoid biosynthetic processes, and localises to the ER membrane. Studies of related genes in other species link the family to the hydroxylation steps of sesquiterpene lactone biosynthesis.
Annotations
- Chromosome
- 8
- GO terms
- lactone anabolism, Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Sesquiterpene Biosynthetic Process, phenylpropanoid anabolism, terpenoid anabolism, Membrane, ER, iron binding
- Publications
- PMID:29758164, PMID:21858047, PMID:37036799, PMID:35630799, PMID:36105709, PMID:35567193, PMID:30468448, PMID:32514287