ALS — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.6HG0611290 (symbol ALS) on barley chromosome 6H encodes an acetolactate synthase, a thiamine pyrophosphate-dependent enzyme. The gene product possesses acetolactate synthase, pyruvate decarboxylase and 2-hydroxyacyl-CoA lyase activities, binds TPP, FAD and magnesium, and localises to the chloroplast stroma as part of the acetolactate synthase complex. ALS is associated with valine and isoleucine biosynthesis, fatty acid alpha-oxidation, inflorescence development, defence response and response to herbicide. In barley, the gene has been connected to imidazolinone sensitivity, tiller formation, herbicide tolerance and aluminium resistance. Studies of related genes in other species link the family to herbicide resistance and tolerance, plant growth, grain yield, drought tolerance and seed production.