sec22 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G28105 (sec22) on chromosome 4 of Fusarium graminearum PH-1 encodes a protein with a Longin domain and a V-SNARE coiled-coil region, and is annotated with palmitoyltransferase activity and syntaxin binding. The gene is associated with SNARE complex function and vesicle fusion, particularly ER-to-Golgi, intra-Golgi, and cis-Golgi-to-rough ER transport, as well as homotypic vacuole fusion, FSM assembly, and protein transport. Its product localizes to the cis-Golgi network membrane, COPII-coated vesicle membrane, Golgi membrane, fungal-type vacuole membrane, endomembrane system, endosome, meiotic spindle pole, medial ring, and cell cortex of cell tips. Studies of related genes in other species link the sec22 family to reduced virulence and fusarium head blight.