TRI1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G00223 (TRI1) on chromosome 1 of Fusarium graminearum PH-1 encodes a cytochrome P450, a heme-binding oxidoreductase with monooxygenase activity that acts on paired donors with incorporation of molecular oxygen. The gene is associated with phytoalexin biosynthesis, gibberellin biosynthesis, mycotoxin anabolism, secondary metabolism, response to mycotoxin, JA signaling, innate immunity, spore germination, sporulation, sexual reproduction, hyphal growth, secretion, and detoxification. Localisation evidence places the product at the ER membrane and membrane. The gene is also associated with glucose and phosphate content. Related genes in other species, including lovA and mokC, link the family to sterol and mycotoxin modifications, though these functions are not established for TRI1 itself.